Congratulations are extended to all participants for their exceptional contributions and remarkable achievements of CBEE faculty and graduate students during the 2023 ACS Conference in San Francisco, CA.
ACS BIOT TANK COMPETITION
Vikash Kumar, chemical and biochemical engineering Ph.D., who emerged victorious at the 2023 BIOT Tank competition, organized by ACS BIOT (Division of Biochemical Technology of the American Chemical Society) at the 2023 ACS conference in San Francisco, CA.
Kumar's company, Breathable Bioprocessing, showcased their groundbreaking solution: a breathable flask paired with a non-invasive sensor system designed for shake flask, t-flask, and G-Rex applications. His innovative solutions in bioprocessing captured the attention of both industry experts and peers, highlighting his commitment to advancing the field.
Watch Vikash’s video here: https://www.linkedin.com/posts/vikashk-as4711_bio-works-x-breathable-bioprocessing-at-acs-biot-activity-7097479059839811584-0t17/
POSTER & ORAL PRESENTATIONS
Hasib Hasan is an Electrical Engineering PhD student advised by Dr. Gary Carter with a research interest in biosensor development and prototyping. Hasib works in CAST under the guidance of Dr. Govind Rao. He did a poster presentation at ACS Conference 2023 on "Machine Learning Techniques in Online Glucose Monitoring Using Glucose Binding Protein-Based Sensor: Application in Bioprocesses".
Poster title: “Machine learning techniques in online glucose monitoring using glucose binding protein-based sensor: Application in bioprocesses”
Vida Rahmatnejad is a chemical and biochemical engineering Ph.D. student advised by Dr. Govind Rao with a research interest in noninvasive process monitoring for cell therapy applications. She presented a talk at ACS Conference on her research titled “Noninvasive Bioprocess Monitoring for Cell Therapy Applications”
Talk Title: Noninvasive Bioprocess Monitoring for Cell Therapy Applications
Tyler R. Josephson, an assistant professor of chemical, biochemical and environmental engineering, captivated the audience with his talk at the ACS Conference.
Talk Title: AI tools for discovering molecular interaction equations
Upal Ghosh, professor of chemical, biochemical and environmental engineering, paid tribute to his former mentor Richard Luthy by organizing a special session at the conference. As a mark of respect and gratitude, Ghosh orchestrated an event that celebrated Luthy's invaluable contributions to the field.
Dr. Blaney, professor of chemical, biochemical and environmental engineering, Dr. He, post doctoral research, '17 chemical and biochemical engineering Ph.D and Sahar Souizi, environmental engineering phd student gave oral presentations at ACS Fall 2023
Blaney, L.; Mangalgiri, K. Photodegradation of antibiotics in the presence of agriculturally-derived organic matter. Fall 2023 ACS National Meeting (San Francisco, CA), August 13-17, 2023.
Souizi, S.; Chen, H.; Stewart, K.; Blaney, L. Sustainable nutrient recovery with novel tube-in-tube Donnan dialysis reactors. Fall 2023 ACS National Meeting (San Francisco, CA), August 13-17, 2023.
He, K.; Liang, J.; Siao, M.; Ellington, M.; Chen, H.; Stewart, K.; Blaney, L. Development of anion-exchange membranes as passive samplers for diverse per- and polyfluoroalkyl substances. Fall 2023 ACS National Meeting (San Francisco, CA), August 13-17, 2023.
A big congratulations to Vikash Kumar, chemical and biochemical engineering Ph.D., who emerged victorious at the 2023 BIOT Tank competition, organized by ACS BIOT (Division of Biochemical Technology of the American Chemical Society) at the 2023 ACS conference in San Francisco, CA.
BIOT Tank is ACS BIOT’s version of “Shark Tank”, where cutting edge start-ups in the fields of bioprocessing compete for the finale with their product and their business plan. There were more than twenty submissions for the 2023 competition, and four were selected to give their final pitch during ACS Fall 2023 in San Francisco. Unlike the other “Shark Tank”, ACS BIOT has two awards instead of investors investing, a judge’s choice award and an audience choice award. It provides a great platform for Vikash Kumar and team to reach a wider and like-minded audience which is an investment of its own kind. We won the audience choice awards. We were the only student team at the competition. The other teams giving their pitch, were established start-ups with millions in funding and an experienced team.
Kumar's company, Breathable Bioprocessing, showcased their groundbreaking solution: a breathable flask paired with a non-invasive sensor system designed for shake flask, t-flask, and G-Rex applications. His innovative solutions in bioprocessing captured the attention of both industry experts and peers, highlighting his commitment to advancing the field.
Watch Vikash’s video here: https://www.linkedin.com/posts/vikashk-as4711_bio-works-x-breathable-bioprocessing-at-acs-biot-activity-7097479059839811584-0t17/
Abstract:
Small-scale bioreactors like shake flasks, t-flasks, and G-rex are extensively used in upstream bioprocessing at academic labs and biopharma companies. However, their inability to support process monitoring due to design constraints and sterile requirements has made them function as black boxes during cell culture, leading to inefficiencies and inconsistent product quality.
To address these issues, a novel breathable membrane-based technology has been developed. This breakthrough allows for non-invasive monitoring of critical process parameters, such as dissolved oxygen and dissolved carbon dioxide, from the external environment of the vessels. For shake flasks, a breathable shake flask has been introduced, enabling measurements of dissolved O2 and CO2 through externally attached sensors. As for T-flasks and G-Rex, a sensor manifold placed at the bottom of the flask facilitates non-invasive monitoring of O2 and CO2 through gas diffusion processes without compromising the integrity of the ongoing processes.
This technological breakthrough promises to revolutionize bioprocessing by providing vital process knowledge and control. As a recent startup with three employees, the company is in early discussions with potential customers and collaborators to expand the technology's implementation globally. This innovation is expected to significantly improve the efficiency and reliability of bioprocessing studies, leading to better therapeutic product outcomes.
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