UMBC’s Lavik and team develop new approach to stop bleeding
Excerpt from "UMBC’s Lavik and Bieberich develop new approach to nanoparticles that stop internal bleeding"
SCIENCE & TECHNOLOGY | NOVEMBER 23, 2021 | MEGAN HANKS
When a person experiences a trauma that leads to significant bleeding, the first few minutes are critical. It’s important that they receive intravenous medication quickly to control the bleeding, but delivering the medication at the right rate can prove challenging. Slower infusions can cause fewer negative reactions, but the medication might not work fast enough, particularly in the case of a serious trauma.
Four UMBC researchers have developed a unique way of modifying the surfaces of nanoparticles within these life-saving medications to provide infusions that can be delivered more quickly, but with a reduced risk of negative reactions. Infusion reactions can cause a range of symptoms, such as rashes and inflammatory responses. This can include anaphylaxis, a life-threatening respiratory failure. Up until this point, the seriousness of these reactions has limited the use of promising nanomedicines, and reducing the likelihood of adverse reactions could be game-changing.
The core of the issue
In a paper recently published in
Nano Letters,
Erin Lavik, professor of chemical, biochemical, and environmental engineering; Chuck Bieberich, professor of biological sciences;
Nuzhat Maisha, Ph.D. ‘21, chemical engineering; and Michael Rubenstein, M.S. ‘14, Ph.D. ‘22, biological sciences, discuss their novel approach to the research. They focused on the core material of the nanoparticles delivered to patients.
“We found that using a polyurethane core reduced the markers associated with infusion reactions,” explains Lavik, who is also the associate dean for research and faculty development in UMBC’s College of Engineering and Information Technology.
Currently, 7% of people experience infusion reactions, the authors note in their paper. “These reactions…limit the treatments available in a substantial portion of patients,” they explain.
“We, like most of the field, have spent a lot of time trying to modify the surfaces of nanoparticles to modulate the reaction,” says Lavik. She shares that while that approach does help to a degree, going a step further by changing the core material appears to have a greater impact.
The research conducted by Lavik, Bieberich, and their colleagues lays the groundwork for future testing of preclinical models using nanocapsules to stop internal bleeding. Lavik explains that collaboration was an important element of this work, especially being able to conduct the research in UMBC’s Interdisciplinary Life Sciences Building.
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Excerpt from "UMBC’s Lavik and Bieberich develop new approach to nanoparticles that stop internal bleeding" SCIENCE & TECHNOLOGY | NOVEMBER 23, 2021 | MEGAN HANKS When a person...
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Mon, 06 Dec 2021 14:02:12 -0500
Continued success at 3MT for PhD students in CBEE
Congratulations to Jahir Antonio Batista Andrade, PhD student in Dr. Lee Blaney's lab.
Jahir continues the excellent track record of CBEE PhD student participation and success in the UMBC and regional
3MT competition.
Jahir competed in the Regional 3MT competition in February 2021 at the Conference of Southern Graduate Schools. His presentation was titled 'Environmental Forensic Tools to Detect Leaking Sewers'. In order to advance to the Regional 3MT competion, Jahir completed and won UMBC's 3MT virtual competion.
3MT celebrates the exciting research conducted by Ph.D. students. Developed by The University of Queensland, the exercise cultivates students’ academic, presentation, and research communication skills. The competition supports their capacity to effectively explain their research in three minutes, in a language appropriate to a non-specialist audience.
Excerpt from Program:
Scott Banta ’97, chemical engineering, is currently
professor and vice-chair for the Department of
Chemical Engineering at Columbia University,
where his research program focuses on protein engineering, metabolic
engineering and synthetic biology.
The Banta lab at Columbia has published more than 100 peer-reviewed
manuscripts, holds nine U.S. patents, and has given seminars around the
country and internationally. Banta co-founded the start-up Ironic Chemicals
LLC and the company went on to receive two grants from the National
Science Foundation.
Banta’s dedication to his field is clear. He served as program chair of the
Bioengineering Area of the Food, Pharmacetical, and Bioengineering
Division for the American Institute of Chemical Engineers (AIChE). Last
year he also delivered a Plenary Award Lecture for the Division. He is an
associate editor for the Biochemical Engineering Journal and part of the
Editorial Advisory Board for the AIChE Journal. He is also heavily involved
in the Biochemical Technology (BIOT) division at the American Chemical
Society. Banta served as the program chair for the National Meeting and
eventually served as the chairman of the BIOT Division and is currently a
long range program coordinator. Additionally, he was inducted into the
College of Fellows by the American Institute for Medical and Biological
Engineering (AIMBE).
Through Banta’s many professional roles and accomplishments, he
continues to contribute to the discussion around critical issues at
the undergraduate and graduate levels to help improve engineering
educational programs.
Left to right: Dr. Freeman A. Hrabowski, Dr. Scott Banta ’97, Dr. Mark Marten
Brian Frazee ’11, M.P.P. ’12
A PhD student is sought for Fall 2022 to carry out a PhD project under Dr. Tyler Josephson's guidance on developing and applying molecular simulation techniques and artificial intelligence tools to gain molecular-scale insights on processes in the environment to enable new solutions for cleaner air and water.
Applicants should have a Masters or Bachelor’s degree in a related field and can apply to either the Environmental Engineering PhD program or the Chemical & Biochemical Engineering PhD program
Environmental Engineering PhD Program Overview
Applicant's prior coursework must include the completion of key prerequisites courses with a B or better. The prospective students must be admitted to the Environmental Engineering Doctoral program at University of Maryland, Baltimore County in the Department of Chemical, Biochemical and Environmental Engineering
Chemical & Biochemical Engineering PhD Program Overview
Applicant's prior coursework must include the completion of key prerequisites courses with a B or better. The prospective students must be admitted to the Chemical & Biochemical Engineering Doctoral program at University of Maryland, Baltimore County in the Department of Chemical, Biochemical and Environmental Engineering
Benefits:
Full-time PhD students admitted to the department are paid a stipend plus tuition remission and health insurance. The Fall 2022 PhD stipend is of $34,967/year.
Application Deadline: January 1, 2022
~~ UMBC is an EEO/AA employer. Individuals with disabilities, veterans, women and minorities are encouraged to apply. ~~
]]>
A PhD student is sought for Fall 2022 to carry out a PhD project under Dr. Tyler Josephson's guidance on developing and applying molecular simulation techniques and artificial intelligence tools...
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Tue, 09 Nov 2021 07:33:54 -0500
Tue, 09 Nov 2021 07:34:27 -0500
UMBC wins 2nd place in AIChE National Jeopardy competition
Over the weekend, UMBC's American Institute of Chemical Engineers (AIChE) ChemE Jeopardy team returned to the National competition and came home with second place in the National Championship, for the second year in a row.
The 2021 national competition team members were:
-
John Laporte, Chemical Engineering, Biotechnology & Bioengineering track;
Sumana Peddibhotla, Chemical Engineering, Biotechnology & Bioengineering track;
-
Erin Huber, Chemical Engineering, Traditional track;
-
Max Bobbin, Chemical Engineering, Environmental Engineering & Sustainability track.
To prepare for this year's competition, the team practiced virtually and in person regularly with other students in the department and were coached by Dr. Neha Raikar.
The AIChE ChemE Jeopardy team is part of the UMBC AIChE Student Chapter that houses ChemE Jeopardy, ChemE Car, and ChemE-Sports; co-advised by Dr. Mariajosé Castellanos and Dr. Neha Raikar.
The team reached the national competition after winning the AIChE Regional competition in April 2021. There are nine AIChE Student Chapter Regions, with approximately fifty teams total. UMBC belongs to the Mid-Atlantic Region. The national competition took place in Boston, MA at the 2021 AIChE Annual Student Conference. The team made it through two rounds of competition, including a tie breaker, to reach the finals.
In the finals, UMBC faced off against Iowa State and University of Iowa. We are so proud of the UMBC-CBEE team members and the continued success in the AIChE Jeopardy competition!
READ MORE
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Over the weekend, UMBC's American Institute of Chemical Engineers (AIChE) ChemE Jeopardy team returned to the National competition and came home with second place in the National Championship, for...
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Mon, 08 Nov 2021 13:01:54 -0500
Fri, 30 Aug 2024 10:23:04 -0400
Alumni Speaker Series [Recording]
Dr. Trevor Needham, Ph.D.'19, & Haley Hartney '19, M.S. '20
We had a great conversation with Trevor Needham, Ph.D.'19, environmental engineering and Haley Hartney '19 chemical engineering, M.S. '20, environmental engineering on Tuesday, November 2, 2021 as part of the Alumni Speaker Series
The
recording is available to those with UMBC credentials.
Speakers
Trevor Needham, Ph.D.'19, environmental engineering.
Trevor Needham is a Hydrologist with the U.S. Geological Survey in the Maryland Water Science Center. His work and research focus on the fate, transport, and remediation of legacy organic contaminants in the complex environmental systems. He holds a Ph.D. in Environmental Engineering from the University of Maryland Baltimore County (2019), a M.S. of Environmental Engineering from the University of Missouri Science and Technology (2011), and a B.S. in Chemistry from the University of Scranton. Additionally, he serves as a Lieutenant Colonel in the Army Reserve assigned as an Adjunct Faculty for the U.S. Army Command and General Staff College. He is married to his wife Becky for 14 years and has four children: John Paul (13), Clare (10), Joshua (9), and Kolbe (3).
Haley Hartney '19 chemical engineering, M.S. '20, environmental engineering
Haley Hartney is a Project Manager for the Environmental Compliance department at NAVFAC in DC. She manages the environmental projects for Marine Corp Base Quantico in all of the major media types including wastewater, storm water, air, hazardous waste, and storage tanks. Haley
graduated from UMBC in December 2019 with a BS in Chemical Engineering and in May 2020, with an MS in Environmental Engineering.
Let us know what you’re doing now and share an update
here.
Cameron Sloan
BS Chemical Engineering, Environmental Engineering and
Sustainability Track (2021)
Camerons works for for TSMC - Taiwan Semiconductor Manufacturing Company. He will be trained in Taiwan for 18 months on the processes for semiconductor/integrated circuits industry before returning to Arizona to support a new fabrication opporation to help the US become self sufficient in the semiconductor/integrated circuits industry.
Mohsin Ghazali
BS Chemical Engineering, Traditional Track (2017)
Mohsin is a Chemical Enigneer at Indian Head - Naval Sea Systems Command (NSWC IHD)
Emily (Schultheis) DiBenedetto
BS Chemical Engineering, Traditional Track (2016)
After working as a chemical engineer, doing design work related to commercial-scale biorefining, and becoming a co-inventor on several patents, Emily earned her J.D. from University of Baltimore in 2020. She served as Associate Comments Editor on the University of Baltimore Law Review, President of the Intellectual Property Law Society, and participant in the Legal Data and Design Clinic and Low Income Taxpayer Clinic. She now works as a corporate attorney specializing in patent litigation in Wilmington, DE.
Hannah (Wilson) Song
BS Chemical Engineering, Biotechnology and Bioengineering Track (2010)
After completing her BS in Chemical Engineering (Biology track) in 2010, Hannah Wilson (now Hannah Song) earned a PhD in Chemical and Biological Engineering from the University of Wisconsin-Madison studying pluripotent stem cells, and then a post-doc at Georgia Tech studying therapeutic cell manufacturing. She was recently promoted to Biologist (GS) at the National Institute of Health Center for Cellular Engineering. Her first project, manufacturing engineered T cells to fight liver cancer, is scheduled to start clinical trials this summer. She credits UMBC and the CBEE department for the many wonderful opportunities to become engaged in research, and Dr. Julia Ross in particular for helping discover her love for cells and the immune system.
(Image: This list of UMBC Alumni employers should not be construed as sponsorship, affiliation, or approval by the trademark owner.)
A PhD student is sought for Fall 2022 to carry out a PhD project under Dr. Chris Hennigan's guidance on Air Pollution, Atmospheric Chemistry, and Aerosol Science.
Applicants should have a Masters or Bachelor’s degree in a related field. Their prior coursework must include the completion of key prerequisites courses with a B or better. The prospective students must be admitted to the Environmental Engineering Doctoral program at University of Maryland Baltimore County in the Department of Chemical, Biochemical and Environmental Engineering. Environmental Engineering PhD Program Overview
Benefits:
Full-time PhD students admitted to the department are paid a stipend plus tuition remission and health insurance. The Fall 2022 PhD stipend is of $34,967/year.
Application Deadline: January 1, 2022
~~ UMBC is an EEO/AA employer. Individuals with disabilities, veterans, women and minorities are encouraged to apply. ~~
]]>
A PhD student is sought for Fall 2022 to carry out a PhD project under Dr. Chris Hennigan's guidance on Air Pollution, Atmospheric Chemistry, and Aerosol Science. Applicants should have a...
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Thu, 21 Oct 2021 13:49:06 -0400
Fri, 05 Nov 2021 09:45:23 -0400
Masters Student Trainee opportunity in the urban environment
FALL 2022
UMBC is seeking applicants in the following areas for urban environmental work:
Masters Student Traineeships - iCARE
The
iCARE NRT master’s degree is a 2-year interdisciplinary degree program with a dual mission of diversity, equity, inclusion, and justice combined with research focused on improving the health of Baltimore Harbor as a socioecosystem. Students will be mentored by a UMBC faculty member and a non-academic scientist from a government agency, non-profit, or industry. That research team will be embedded in a larger stakeholder team, meaning that each student and their mentors will identify one or more community members (non-scientists) with a stake in the research to be engaged in the research from development to completion.
Students will also be taking skills courses (community leadership, DEIJ, oral and written communication) and disciplinary courses appropriate to their research project.
Graduate students in our program will follow a two-year schedule that includes a series of professional and disciplinary courses, plus a research project that will comprise their master’s thesis. For the research project, students will be mentored by a team that includes at least one faculty member and one partner practitioner working on projects related to the Baltimore Harbor and surrounding environments.
Student Benefits Include:
- $34,000 annual stipend, full tuition coverage, fees, & health insurance.
- Up to $7,500 in research expenses.
- Mentoring and networking with employers across the environmental sector.
Students should apply to any of the five main departments at UMBC affiliated with the program: Biological Sciences; Chemical, Biochemical and Environmental Engineering; Geography and Environmental Systems; Marine Estuarine Environmental Sciences; or the School of Public Policy. They should also separately complete a short application to the ICARE program, available to view on our website here:
https://icare.umbc.edu/application/.
Here is a link to a
series of slides that describes what each of the ICARE faculty do especially with respect to the ICARE master's program.
Please pass this information on to prospective students and encourage them to contact us and complete the
ICARE Interest Form.
Students need to apply to their respective program at this
link and complete a supplemental
ICARE NRT application by
January 1, 2022 for the
Fall 2022 cohort.
Potential Environmental Engineering Mentors:
- Lee Blaney - contaminants of emerging concern & resource recovery
- Upal Ghosh - analysis and remediation of toxic pollutants in soils and other environments
- Brian Reed - removal of inorganic contaminants from the aqueous phase by activated carbons
- Christopher Hennigan - Processes governing atmospheric chemistry and aerosol pollution
- Claire Welty - quantify and predict the urban hydrologic cycle and coupled biogeochemical cycles from neighborhood to regional scales
Dr. Kafui Dzirasa ‘01, M8, chemical engineering, recently earned two highly prestigious honors distinctive even among leaders in the medical and life sciences: an HHMI Investigator award and election to the National Academy of Medicine.
Dzirasa is the K. Ragna Rama Krishnan Associate Professor of psychiatry and behavioral sciences at Duke University. He earned both his MD and his PhD in neurobiology and neurosciences at Duke. Today, he examines the role of the brain’s electrical activity in psychiatric illness, including depression, bipolar disorder, and addiction, with the goal of creating mechanisms to disrupt these disorders.
Achievement and service
Dzirasa is one of 100 new members
elected to the National Academy of Medicine this year. The announcement recognizes his “seminal contributions to the neuroscience of emotion and mental illness” as well as his pioneering research methods. It also honors his “contributions to society through science policy and advocacy, a commitment to mentoring, and support for efforts to build a diverse and inclusive scientific workforce,” carrying forward the values of UMBC’s Meyerhoff Scholars Program.
Election to the National Academy of Medicine recognizes leaders in health and medicine who have demonstrated both outstanding professional achievement and a commitment to service. The National Academy of Medicine has more than 2,200 elected members worldwide, with new members limited to 100 per year.